Sameer V. Dalvi
Engineering microbubbles for biomedical applications: Microbubbles are colloidal particles with 0.1 to 10 μm diameter and consist of a shell made of lipid or protein molecules. The shell encapsulates a gaseous core containing gases such as Perfluorobutane (PFB), Sulphur Hexafluoride (SF6) or Oxygen (O2). The microbubble shell can contract and expand upon exposure to ultrasound. This phenomenon enables the use of microbubbles in applications such as contrast imaging, sonoporation and as drug/gene delivery vehicles. Our research efforts are focused on synthesis of microbubbles and understanding the effect of shell material, additives, storage medium and transport properties of core gas on the stability and biocompatibility of aqueous microbubble suspensions.
- Associate Professor, Indian Institute of Technology, Gandhinagar (Nov 2015 to present)
- Assistant Professor, Indian Institute of Technology, Gandhinagar (Dec 2009 – Nov 2015)
- Research Scientist, Department of Chemical Engineering, Columbia University (in the City of New York), USA (Jun 2009 – Dec 2009)
- Post-doctoral Research Associate, New Jersey Center for Engineered Particulates (NJCEP), New Jersey Institute of Technology, NJ, USA (Apr 2007 – May 2009)
Selected Recent Publications
- Arul Mozhi Devan Padmanathan, Apoorva Sneha Ravi, Hema Choudhary, Subramanyan Namboodiri Varanakkottu, Sameer Vishvanath Dalvi, “Predictive Framework for the Spreading of Liquid Drops and the Formation of Liquid Marbles on Hydrophobic Particle Bed”, Articles ASAP, Langmuir, 2019
- Indumathi S. and Sameer V. Dalvi, “Crystal Engineering of Curcumin with Salicylic Acid and Hydroxyquinol as Coformers”, Crystal Growth & Design, 2017, 17 (7), pp 3974–3988.
- Awaneesh Upadhyay, Sameer V. Dalvi, Gaurav Gupta and Nitin Khanna, “Effect of PEGylation on Performance of Protein Microbubbles and its Comparison with Lipid Microbubbles”, Materials Science and Engineering C, 71 (2017), pp 425-430.
- Alpana A. Thorat and Sameer V. Dalvi, “Solid-State Phase Transformations and Storage Stability of Curcumin Polymorphs”, Crystal Growth and Design, 15 (4) (2015), pp 1757-1770.
- Sameer V. Dalvi and Jignesh Joshi, “Modeling of Microbubble Dissolution in Aqueous Medium”, Journal of Colloid and Interface Science, 437 (2015), pp 259-269.
- Alpana A. Thorat and Sameer V. Dalvi, “Particle Formation Pathways and Polymorphism of Curcumin Induced by Ultrasound and Additives during Liquid Antisolvent Precpitation”, CrystEngComm, 16 (48) (2014), pp 11102 – 11114.
- Alpana Thorat, Manish D. Yadav and Sameer V. Dalvi, “Simple Criterion for Stability of Aqueous Suspensions of Ultra-fine Particles of a Poorly Water Soluble Drug”, Langmuir, 30 (16) (2014), pp 4576–4592.